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murine knockout styles. cTnT-knockout will cause sarcomere disassembly and early embryonic lethality.18 Remarkably, knockout of cTnI in murine embryos has no impact on overall health before postnatal working day 15, attributable to ssTnI compensating for The dearth of cTnI.
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39 noticed the concentration of cTnT peaking simultaneously as CK-MB (localized within the cytosol), and considering the fact that the release profile of cTnT was biphasic, these observations can not be accounted for by infarct-zone clearance/washout alone.
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